Yes, it is possible. At client-side, you create a <a> link with target='_bank', the href will be pointing to the handle php file. In the handle file, in order to force PDF open in browser instead of downloading you do:

$report->run()->export()->pdf()->toBrowser("myfile.pdf",true);

The second parameter true indicate that file will be open on browser.

Hope that helps.

May I know exactly your issue. Could you please describe the current state.